What does code P0301 mean on a Lexus and is it safe to drive?
P0301: Cylinder 1 Misfire Detected. Here's what it means on your Lexus, what usually causes it, what repairs typically cost, and how safe it is to keep driving.
What this code means
The PCM has detected a misfire specifically on cylinder 1. Similar to P0300, but pinned to a single cylinder.
Common causes for your Lexus
- Worn or fouled spark plug on cylinder 1
- Failing ignition coil or coil-on-plug
- Leaking or clogged fuel injector
- Low compression in cylinder 1
Symptoms
- Check Engine Light (often flashing when misfire is severe)
- Rough idle or shaking, especially at low RPM
- Loss of power under load
Typical fixes
- Replace spark plug and/or coil on cylinder 1
- Test and clean or replace the injector
- Perform compression test and repair internal issues if needed
Repair cost range
For a Lexus, repairs for P0301 often fall between $150 and $900, depending on the cause and whether you use OEM or aftermarket parts. Labor rates vary by location.
Known issues on Lexus
Lexus 2GR-FSE (D-4S dual injection) P0301 is less prone to carbon buildup than pure direct injection engines because port injection keeps valves clean. Cylinder 1 misfire on the 2GR-FSE is typically a failed coil-on-plug. On 2GR-FE (single port injection), carbon is not a factor—coil swap confirms.
Most commonly affected models