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What does code P0303 mean on a Lexus and is it safe to drive?

P0303: Cylinder 3 Misfire Detected. Here's what it means on your Lexus, what usually causes it, what repairs typically cost, and how safe it is to keep driving.

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What this code means

The PCM has detected a misfire specifically on cylinder 3. Diagnosis follows the same steps as P0301—swap parts to the same position on a known-good cylinder to isolate the fault.

Common causes for your Lexus

  • Worn or fouled spark plug on cylinder 3
  • Failing ignition coil on cylinder 3
  • Leaking or clogged fuel injector
  • Low compression on cylinder 3

Symptoms

  • Check Engine Light, often flashing under load
  • Rough idle or shaking
  • Loss of power, hesitation

Typical fixes

  • Replace spark plug and coil on cylinder 3
  • Test and replace fuel injector
  • Compression test if ignition parts don't resolve it

Repair cost range

For a Lexus, repairs for P0303 often fall between $150 and $900, depending on the cause and whether you use OEM or aftermarket parts. Labor rates vary by location.

Known issues on Lexus

Lexus 2GR-FE P0303 rear-bank cylinder follows standard COP diagnosis. Rear-bank coil access on the 2GR-FE requires intake manifold removal—confirm the fault with a front-bank coil swap before disassembly. On GX460 with the 1UR-FE V8, P0303 is uncommon and typically a coil or plug failure.

Most commonly affected models

RX350 2GR-FE 2007–2015ES350 2GR-FE 2007–2012GX460 1UR-FE V8 2010–2023

Is it safe to keep driving your Lexus with this code?

For driving-safety guidance—how far you can go, when to tow, and what's urgent—see these checklists:

Browse P0303 on your Lexus by model year

Year-specific guides include Lexus-tailored causes and repair costs.

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