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What does code P0306 mean on a Lexus and is it safe to drive?

P0306: Cylinder 6 Misfire Detected. Here's what it means on your Lexus, what usually causes it, what repairs typically cost, and how safe it is to keep driving.

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What this code means

Misfire on cylinder 6, found on V6 and V8 engines. On transversely-mounted V6 engines the rear bank cylinders (including cylinder 6) often have higher labor costs due to access difficulty.

Common causes for your Lexus

  • Worn spark plug on cylinder 6
  • Failed coil-on-plug
  • Fuel injector fault
  • Low compression

Symptoms

  • Check Engine Light, may flash under load
  • Rough idle or vibration
  • Hesitation and power loss

Typical fixes

  • Replace spark plug and COP coil on cylinder 6
  • Replace or clean injector on cylinder 6
  • Compression and leak-down test if no improvement

Repair cost range

For a Lexus, repairs for P0306 often fall between $150 and $1200, depending on the cause and whether you use OEM or aftermarket parts. Labor rates vary by location.

Known issues on Lexus

Lexus V8 P0306 on the last rear-bank cylinder is typically a failed COP coil on the 1UR-FE and 3UR-FE. These engines are extremely durable—if a coil fails, it usually means high mileage. OEM Toyota/Lexus coils are recommended; aftermarket coils can cause recurring misfires.

Most commonly affected models

GX460 1UR-FE V8 2010–2023LX570 3UR-FE V8 2008–2021LS460 1UR-FSE V8 2007–2017

Is it safe to keep driving your Lexus with this code?

For driving-safety guidance—how far you can go, when to tow, and what's urgent—see these checklists:

Browse P0306 on your Lexus by model year

Year-specific guides include Lexus-tailored causes and repair costs.

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