What does code P0306 mean on a Mercedes-Benz and is it safe to drive?

P0306: Cylinder 6 Misfire Detected. Here's what it means on your Mercedes-Benz, what usually causes it, what repairs typically cost, and how safe it is to keep driving.

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What this code means

Misfire on cylinder 6, found on V6 and V8 engines. On transversely-mounted V6 engines the rear bank cylinders (including cylinder 6) often have higher labor costs due to access difficulty.

Common causes for your Mercedes-Benz

  • Worn spark plug on cylinder 6
  • Failed coil-on-plug
  • Fuel injector fault
  • Low compression

Symptoms

  • Check Engine Light, may flash under load
  • Rough idle or vibration
  • Hesitation and power loss

Typical fixes

  • Replace spark plug and COP coil on cylinder 6
  • Replace or clean injector on cylinder 6
  • Compression and leak-down test if no improvement

Repair cost range

For a Mercedes-Benz, repairs for P0306 often fall between $150 and $1200, depending on the cause and whether you use OEM or aftermarket parts. Labor rates vary by location.

Known issues on Mercedes-Benz

Mercedes M272/M273 P0306 on the rear-most cylinder follows the same diagnosis as other cylinders on these engines. On M273 V8 S550 and GL450, P0306 is typically a failed coil—the M273 does not have the same balance shaft issues as the M272.

Most commonly affected models

E350 M272 2006–2012GL450 M273 2007–2012S550 M273 2007–2013

Is it safe to keep driving your Mercedes-Benz with this code?

For driving-safety guidance—how far you can go, when to tow, and what's urgent—see these checklists:

Browse P0306 on your Mercedes-Benz by model year

Year-specific guides include Mercedes-Benz-tailored causes and repair costs.

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