2021 Nissan P0303: What It Means & Is It Safe to Drive?

P0303 on the 2021 Nissan: Cylinder 3 Misfire Detected. Here's what it means, what usually causes it, what repairs typically cost, and whether it's safe to keep driving.

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What this code means

The PCM has detected a misfire specifically on cylinder 3. Diagnosis follows the same steps as P0301—swap parts to the same position on a known-good cylinder to isolate the fault.

Common causes on the 2021 Nissan

  • Worn or fouled spark plug on cylinder 3
  • Failing ignition coil on cylinder 3
  • Leaking or clogged fuel injector
  • Low compression on cylinder 3

Symptoms

  • Check Engine Light, often flashing under load
  • Rough idle or shaking
  • Loss of power, hesitation

Typical fixes

  • Replace spark plug and coil on cylinder 3
  • Test and replace fuel injector
  • Compression test if ignition parts don't resolve it

Repair cost range

For a 2021 Nissan, repairs for P0303 typically fall between $150 and $900, depending on the root cause and labor rates in your area.

Known issues on Nissan

Nissan VQ35DE P0303 is a rear-bank cylinder requiring intake plenum removal for coil access. Confirm the fault with a scan tool before disassembly. On VQ40 V6 in Pathfinder and Frontier, rear-bank coils fail due to heat proximity to the firewall.

Most commonly affected models

Maxima VQ35DE 2004–2008350Z VQ35DE 2003–2006Pathfinder VQ40 2005–2012

Is it safe to keep driving your 2021 Nissan with this code?

For driving-safety guidance—how far you can go, when to tow, and what's urgent—see these checklists:

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