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What does code P0301 mean on a Ram and is it safe to drive?

P0301: Cylinder 1 Misfire Detected. Here's what it means on your Ram, what usually causes it, what repairs typically cost, and how safe it is to keep driving.

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What this code means

The PCM has detected a misfire specifically on cylinder 1. Similar to P0300, but pinned to a single cylinder.

Common causes for your Ram

  • Worn or fouled spark plug on cylinder 1
  • Failing ignition coil or coil-on-plug
  • Leaking or clogged fuel injector
  • Low compression in cylinder 1

Symptoms

  • Check Engine Light (often flashing when misfire is severe)
  • Rough idle or shaking, especially at low RPM
  • Loss of power under load

Typical fixes

  • Replace spark plug and/or coil on cylinder 1
  • Test and clean or replace the injector
  • Perform compression test and repair internal issues if needed

Repair cost range

For a Ram, repairs for P0301 often fall between $150 and $900, depending on the cause and whether you use OEM or aftermarket parts. Labor rates vary by location.

Known issues on Ram

Ram 5.7L HEMI P0301 can indicate an MDS lifter collapse on cylinder 1, one of the four deactivation cylinders. Check for oil consumption and a ticking noise before replacing the coil. On 3.6L Pentastar Ram 1500, the cam follower wear issue applies—swap the coil first, then inspect the follower if a tick is present.

Most commonly affected models

Ram 1500 5.7L HEMI 2009–2021Ram 1500 3.6L Pentastar 2012–2021Ram 2500 6.4L HEMI 2014–2021

Is it safe to keep driving your Ram with this code?

For driving-safety guidance—how far you can go, when to tow, and what's urgent—see these checklists:

Browse P0301 on your Ram by model year

Year-specific guides include Ram-tailored causes and repair costs.

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