2019 Mercedes-Benz P0301: What It Means & Is It Safe to Drive?

P0301 on the 2019 Mercedes-Benz: Cylinder 1 Misfire Detected. Here's what it means, what usually causes it, what repairs typically cost, and whether it's safe to keep driving.

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What this code means

The PCM has detected a misfire specifically on cylinder 1. Similar to P0300, but pinned to a single cylinder.

Common causes on the 2019 Mercedes-Benz

  • Worn or fouled spark plug on cylinder 1
  • Failing ignition coil or coil-on-plug
  • Leaking or clogged fuel injector
  • Low compression in cylinder 1

Symptoms

  • Check Engine Light (often flashing when misfire is severe)
  • Rough idle or shaking, especially at low RPM
  • Loss of power under load

Typical fixes

  • Replace spark plug and/or coil on cylinder 1
  • Test and clean or replace the injector
  • Perform compression test and repair internal issues if needed

Repair cost range

For a 2019 Mercedes-Benz, repairs for P0301 typically fall between $150 and $900, depending on the root cause and labor rates in your area.

Known issues on Mercedes-Benz

Mercedes M272 V6 P0301 is often related to the balance shaft gear failure—a known and expensive issue on M272 engines built before 2008. A worn balance shaft gear can cause timing irregularities that trigger cylinder-specific misfires. Verify balance shaft timing before condemning the ignition system.

Most commonly affected models

C300 M272 2007–2012E350 M272 2006–2012ML350 M272 2006–2011

Is it safe to keep driving your 2019 Mercedes-Benz with this code?

For driving-safety guidance—how far you can go, when to tow, and what's urgent—see these checklists:

See all codes for your Mercedes-Benz

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